For 340B hospitals, the risk of an audit has never been greater. The Health Resources and Services Administration (HRSA) has doubled the number of audits from 99 in fiscal year (FY) 2014 to 217 for FY 2015. This number is sure to increase in FY 2016, making 340B audit readiness a top-of-mind concern for 340B hospital C-suite executives and pharmacy leadership.